The lineage that results from recombination is called a “recombinant.” This may occur when a person is infected with two variants at the same time. Recombination: A process in which the genomes of two SARS-CoV-2 variants combine during the viral replication process to form a new variant that is different from both parent lineages.SARS-CoV-2 Interagency Group (SIG) as a Variant of Interest (VOI), Variant of Concern (VOC), Variant of High Consequence (VOHC) or Variant Being Monitored (VBM) due to shared attributes and characteristics that may require public health action. In some cases, a lineage or group of lineages with similar genetic changes, may be designated by the World Health Organization (WHO) or the U.S. Variant: A variant is a viral genome (genetic code) that may contain one or more mutations.For example, BA.2.75 is a sublineage of BA.2. Sublineage: A term used to define a lineage as it relates to being a direct descendent of a parent lineage.SARS-CoV-2 has many lineages all cause COVID-19. Lineage: A lineage is a group of closely related viruses with a common ancestor.Mutations happen frequently, but only sometimes change the characteristics of the virus. Mutation: A mutation refers to a single change in a virus’s genome (genetic code).
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